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Product Information
Description |
Neuropilin 1 rabbit polyclonal antibody |
Protein full name |
Neuropilin-1 |
Synonyms |
A5 protein, CD304, Nrp1, Nrp |
Immunogen |
Recombinant protein corresponding to Mouse Neuropilin 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell Membrane |
Uniprot ID |
P97333, Q9QWJ9 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 1300-1: 2800 |
brain, liver cancer |
Background
Neuropilin 1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor and semaphorin family members. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2.
Images
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Immunohistochemistry of paraffin embedded mouse brain using NRP1 (GB111325) at dilution of 1:1400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using NRP1 (GB111325) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded human liver cancer using NRP1 (GB111325) at dilution of 1:1300 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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