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Anti -Ephrin B1 Rabbit pAb

價格: 在線咨詢
貨號:
KT011654
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Ephrin B1 rabbit polyclonal antibody

Protein full name

Ephrin-B1

Synonyms

EFL-3, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1, EFL3, EPLG2, LERK2

Immunogen

Recombinant protein corresponding to Mouse Ephrin B1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

38 kDa

Observed MW.

45 kDa

Uniprot ID

P98172




Applications


Applications

Species

Dilution

Positive Sample

WB

Human

1: 500-1: 1000

PC-3, Hacat, HepG2




Background


Ephrin-B1, also known as LERK-2, ELK-L, EFL-3, Cek5-L, and STRA-1 , is a member of the ephrin ligand family which binds members of the Eph receptor family. Several signaling molecules have been shown to interact with the cytoplasmic region, although specific signaling roles have yet to be elucidated. Ephrin-B1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse Ephrin-B1 share 94% amino acid identity. Only membrane-bound or Fc-clustered ligands are capable of activating the receptor in vitro. Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation. In vivo, the ligands and receptors display reciprocal expression. It has been found that nearly all receptors and ligands are expressed in developing and adult neural tissue. The Eph/ephrin families also appear to play a role in angiogenesis.




Images


Picture 1.png

Western blot analysis of EphrinB1 (GB111417) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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