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Anti -CBLN2 Rabbit pAb

價格: 在線咨詢
貨號:
KT011672
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CBLN2 rabbit polyclonal antibody

Protein full name

Cerebellin-2

Synonyms

Cbln2, Cerebellin 2 Precursor

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CBLN2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

Q8IUK8, Q8BGU2, P98087




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 300-1: 600

brain




Background

Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human brain using CBLN2 (GB111673) at dilution of 1:300 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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