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Product Information
Description |
RAB3GAP1 rabbit polyclonal antibody |
Protein full name |
Rab3 GTPase-activating protein catalytic subunit |
Synonyms |
RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, Rab3gap1, Kiaa0066, WARBM1 |
Immunogen |
Recombinantproteincorresponding to Mouse RAB3GAP1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
110 kDa |
Observed MW. |
130 kDa |
Uniprot ID |
Q15042, Q80UJ7, P69735 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, kidney |
Background
RAB3GAP1 (RAB3 GTPase-activating protein 1) is the catalytic subunit of the heterodimeric enzyme RAB3GAP (RAB3GTPase-activating protein), a key regulator of the RAB3 cycle, which controls calcium-mediated exocytosis of neurotransmitters and hormones. Mutations in RAB3GAP1 cause Warburg Micro syndrome and Martsolf syndrome , phenotypically overlapping autosomal recessive conditions characterized by ocular and neurodevelopmental manifestations.
Images
|
Western blot analysis of Rab3GAPp130 (GB111705) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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