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Anti -GDNF Receptor alpha 2/GFRA2 Rabbit pAb

價格: 在線咨詢
貨號:
KT011675
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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Product Information


Description

GDNF Receptor alpha 2/GFRA2 rabbit polyclonal antibody

Protein full name

GDNF family receptor alpha-2

Synonyms

GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NTNR-alpha, Gfra2, Gdnfrb, Trnr2

Immunogen

Recombinant protein corresponding to Mouse GDNF Receptor alpha 2/GFRA2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

52 kDa

Observed MW.

52 kDa

Uniprot ID

O00451, O08842




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, placenta, liver




Background


GFRA2, also named as GDNFRB, RETL2 and TRNR2, belongs to the GDNFR family. It is a receptor for neurturin. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is a potent survival factor for central dopaminergic neurons, motor neurons, and several other populations of neurons in the central and peripheral nervous systems. The GDNF signal is mediated by a complex of the receptor tyrosine kinase RET and a glycosylphosphatidylinositol (GPI)-linked protein, GDNFRA. GFRA2 has three isoforms with MW 34-36 kDa, 39-41 kDa and 50-55 kDa. This antibody recognizes all the three isoforms.




Images


Picture 1.png

Western blot analysis of GDNFReceptora2 (GB111764) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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