Anti -MAG/GMA Rabbit pAb

價格：在線咨詢

貨號：

KT011689

產(chǎn)品規(guī)格：

100ul

Applications：

WB/IHC/IF

Species：

M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	MAG/GMA rabbit polyclonal antibody
Protein full name	Myelin-associated glycoprotein
Synonyms	Siglec-4a, Mag, GMA, S-MAG, SIGLEC4A, SPG75, Sialic acid binding Ig like lectin 4A
Immunogen	Recombinant protein corresponding to Mouse MAG
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Predicted MW.	69 kDa
Observed MW.	100 kDa
Uniprot ID	P20917, P07722

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 1000-1: 2000	brain, cortex, cerebellum, spinal cord
IHC/IF	Mouse, Rat	1: 300-1: 1200	brain

Background

MAG (myelin associated glycoprotein) is a Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha2,3-linked sialic acid. Isoform L-MAG is critical for the formation of myelin in the CNS, whereas isoform S-MAG is sufficient to maintain the integrity of myelin in PNS. Binds to RTN4R. Isoform S-MAG is the predominant isoform in CNS and PNS of the adult. In CNS isoform L-MAG is the major form synthesized early in development, and it persists as a significant proportion of the MAG present in the adult.

Images

	Western blot analysis of MAG (GB112158) at dilution of 1: 1000
	Immunohistochemistry of paraffin embedded mouse brain using MAG (GB112158) at dilution of 1: 600 (300x lens)
	Immunohistochemistry of paraffin embedded rat brain using MAG (GB112158) at dilution of 1: 600 (300x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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