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Anti -CRMP3 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011715
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

CRMP3 rabbit polyclonal antibody

Protein full name

Dihydropyrimidinase-related protein 4

Synonyms

DRP-4, Collapsin response mediator protein 3, CRMP-3, UNC33-like phosphoprotein 4, ULIP-4, Dpysl4, Crmp3, Ulip4

Immunogen

Recombinant protein corresponding to Mouse CRMP3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

O35098, Q62951




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 600-1: 3000

brain, cervical cancer, epencephalon, laryngocarcinoma, ovary




Background


CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.




Images


Immunohistochemistry of paraffin embedded mouse brain using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunohistochemistry of paraffin embedded mouse epencephalon using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunohistochemistry of paraffin embedded rat epencephalon using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunofluorescence of paraffin embedded human cervical cancer using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunofluorescence of paraffin embedded human laryngocarcinoma using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunofluorescence of paraffin embedded mouse brain using CRMP3 (GB112592) at dilution of 1:650 (400x lens)

Immunofluorescence of paraffin embedded mouse ovary using CRMP3 (GB112592) at dilution of 1:650 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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