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Product Information
Description |
CNTFR rabbit polyclonal antibody |
Protein full name |
Ciliary neurotrophic factor receptor subunit alpha |
Synonyms |
CNTF receptor subunit alpha, CNTFR-alpha, CNTFR |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CNTFR |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
41 kDa |
Observed MW. |
45 kDa |
Uniprot ID |
P26992, O88507, Q08406 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
heart, liver, brain, liver cancer |
Background
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
Images
Western blot analysis of CNTFR (GB112629) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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