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Anti -TNR Rabbit pAb

價格: 在線咨詢
貨號:
KT011721
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

TNR rabbit polyclonal

Protein full name

Tenascin-R

Synonyms

TN-R, Janusin, Neural recognition molecule J1-160/180, Restrictin, Tnr

Immunogen

Recombinant protein corresponding to

Mouse TNR

Isotype

IgG

Purity

Affinity purification

Predicted MW.

150 kDa

Observed MW.

170 kDa

Uniprot ID

Q92752Q8BYI9Q05546




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 300-1: 600

pancreas, cerebellum, brain




Background


TNR, also named as Restrictin and Janusin, belongs to the tenascin family. Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides, TNR inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2 (FAK) phosphorylation and cell detachment.




Images



Western blot analysis of TNR (GB112795) 

at dilution of 1: 600

Lane 1: U87 cell lysate

Lane 2: THP-1 cell lysate

Lane 4: Mouse pancreas tissue lysate

Lane 5: Mouse cerebellum tissue lysate

Lane 6: Rat brain tissue lysate

Lane 7: Rat pancreas tissue lysate






Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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