Anti -TrkB Rabbit pAb

價格：在線咨詢

貨號：

KT011726

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	TrkB rabbit polyclonal antibody
Protein full name	BDNF/NT-3 growth factors receptor
Synonyms	NTRK2, GP145-TrkB, TRKB, trk-B, neurotrophic receptor tyrosine kinase 2, OBHD
Immunogen	Recombinant protein corresponding to Mouse TRKB
Isotype	IgG
Purity	Affinity purification
Predicted MW.	92 kDa
Observed MW.	90/140 kDa
Uniprot ID	P15209, Q63604, Q16620

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	HepG2, HACAT, SH-SY5Y, liver, brain, spinal marrow

Background

Tropomyosin receptor kinase B is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The neurotrophins that activate TrkB are: BDNF (Brain Derived Neurotrophic Factor), neurotrophin-4 (NT-4), andneurotrophin-3 (NT-3). As such, TrkB mediates the multiple effects of these neurotrophic factors, which includes neuronal differentiation and survival. Research has shown that activation of the TrkB receptor can lead to down regulation of the KCC2 chloride transporter in cells of the CNS.

Images

Picture 1.png

Western blot analysis of TRKB (GB11295-1) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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