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Product Information
Description |
ARMET/ARP rabbit polyclonal |
Protein full name |
Mesencephalic astrocyte-derived neurotrophic factor |
Synonyms |
Arginine-rich protein, ARMET, ARP, MANF, Protein ARMET |
Immunogen |
Recombinant protein corresponding to Mouse ARMET/ARP |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
20 kDa |
Observed MW. |
20 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
testis, pancreas |
Background
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Images
Western blot analysis of ARMET (GB113576) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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