KLH conjugated Synthetic peptide corresponding to Mouse FABP-1
Isotype
IgG
Purity
Affinity purification
Predicted MW.
14 kDa
Observed MW.
14 kDa
Uniprot ID
P12710, P02692
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 300-1: 600
liver
Background
Fatty acid binding proteins (FABP) are small intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellulair utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of ischemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.
Images
Western blot analysis of FABP1 (GB111152) at dilution of 1: 300
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .