Anti -HIF3 alpha/IPAS Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT012044

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	HIF3 alpha rabbit polyclonal antibody
Protein full name	Hypoxia-inducible factor 3-alpha
Synonyms	HIF3-alpha, bHLHe17, HIF3-alpha-1, PASD7, IPAS, Member of PAS protein 7, BHLHE17, HIF3A, MOP7
Immunogen	Recombinant protein corresponding to Mouse HIF3 alpha
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	Q9Y2N7

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1: 800-1: 3000	kidney, liver, lung

Background

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Images

	Immunohistochemistry of paraffin embedded mouse kidney using HIF-3α (GB111175) at dilution of 1:1600 (400x lens)
	Immunohistochemistry of paraffin embedded mouse liver using HIF-3α (GB111175) at dilution of 1:1600 (400x lens)
	Immunohistochemistry of paraffin embedded mouse lung using HIF-3α (GB111175) at dilution of 1:1600 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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