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Anti -RNF7 Rabbit pAb

價格: 在線咨詢
貨號:
KT012197
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

RNF7 rabbit polyclonal antibody

Protein full name

RING-box protein 2

Synonyms

Rbx2, RING finger protein 7, Sensitive to apoptosis gene protein, Rnf7, Rbx2, Sag

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse RNF7

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q9UBF6, Q9WTZ1




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

colon, embryonic mouse, heart, lung, testis




Background


The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.




Images


Immunohistochemistry of paraffin embedded human colon using RNF7 (GB111234) at dilution of 1:1000 (400x lens)

Immunohistochemistry of paraffin embedded mouse testis using RNF7 (GB111234) at dilution of 1:1000 (300x lens)

Immunohistochemistry of paraffin embedded rat testis using RNF7 (GB111234) at dilution of 1:1000 (400x lens)

Immunofluorescence of paraffin embedded mouse embryonic mouse using RNF7 (GB111234) at dilution of 1:2000 (400x lens)

Immunofluorescence of paraffin embedded mouse heart using RNF7 (GB111234) at dilution of 1:2000 (400x lens)

Immunofluorescence of paraffin embedded rat lung using RNF7 (GB111234) at dilution of 1:2000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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