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Anti -Cyclophilin A Rabbit pAb

價格: 在線咨詢
貨號:
KT012198
產(chǎn)品規(guī)格:
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Cyclophilin A rabbit polyclonal antibody

Protein full name

Peptidyl-prolyl cis-trans isomerase A

Synonyms

PPIase A, Cyclophilin A, Ppia, Cyclosporin A-binding protein, Rotamase A, SP18

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclophilin A

Isotype

IgG

Purity

Affinity purification

Predicted MW.

18 kDa

Observed MW.

18 kDa

Uniprot ID

P62937, P17742, P10111




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, brain, thymus




Background


Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.




Images


Picture 1.png

Western blot analysis of cyclophilin-A (GB111283) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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