Anti -FBXW4 Rabbit pAb

價格：在線咨詢

貨號：

KT012226

產(chǎn)品規(guī)格：

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	FBXW4 rabbit polyclonal
Protein full name	F-box/WD repeat-containing protein 4
Synonyms	F-box and WD-40 domain-containing protein 4, Protein hagoromo, Fbxw4, Fbw4, SHFM3, DAC, Dactylin, FBWD4
Immunogen	Recombinant protein corresponding to Mouse FBXW4
Isotype	IgG
Purity	Affinity purification
Predicted MW.	46 kDa
Observed MW.	46 kDa
Uniprot ID	Q9JMJ2

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 1000-1: 2000	skeletal muscle, heart

Background

F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

Images

Western blot analysis of FBXW4 (GB113059)

at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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