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Anti -beta Actin Rabbit pAb

價格: 在線咨詢
貨號:
DRF1019
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H,M,R
購買數(shù)量:
立即詢價 在線咨詢 400-1016-218
產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

beta Actin rabbit polyclonal

Protein full name

Actin, cytoplasmic 1

Synonyms

ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin beta, Beta Cytoskeletal Actin 

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse β-Actin

Isotype

IgG

Predicted MW.

42 kDa

Observed MW.

45 kDa

Purity

Affinity purification

Uniprot ID

P60709, P60710, P60711



Applications



Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1:1000-1:2000

lung, kidney, brain





Background


Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility .




Images


Western blot analysis of β-Actin (GB11001) at dilution of 1: 2000

Lane 1: U251 cell lysate

Lane 2: N2A cell lysate

Lane 3: c6 cell lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse kidney tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat kidney tissue lysate

Lane 9: Rat brain tissue lysate



Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.

Storage Buffer

PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .



Publications:


Title

Journal

Pubmed ID

Application

1

Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.

Theranostics

33500732

WB

2

STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells.

Journal of Immunology Research

33062724

WB

3

Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis via the MAPK/ERK Pathway.

Frontiers in Pharmacology

33041790

WB

4

Conductive Hydroxyethyl Cellulose/Soy Protein Isolate/Polyaniline Conduits for Enhancing Peripheral Nerve Regeneration via Electrical Stimulation.

Frontiers in Bioengineering and Biotechnology

32719783

WB

5

Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI.

Theranostics

32641990

WB

6

Effects of electrical stimulation on cell activity, cell cycle, cell apoptosis and βcatenin pathway in the injured dorsal root ganglion cell.

Molecular Medicine Reports

32323840

WB

7

Prognostic values of immune scores and immune microenvironment-related genes for hepatocellular carcinoma.

Aging (Albany NY)

32213661

WB

8

Chronic sleep fragmentation shares similar pathogenesis with neurodegenerative diseases: Endosome-autophagosome-lysosome pathway dysfunction and microglia-mediated neuroinflammation.

CNS Neuroscience Therapeutics

31549780

WB

9

High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats.

Oxidative Medicine and Cellular Longevity

31998444

WB

10

High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.

Mediators of Inflammation

31933540

WB 


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