服務(wù)熱線
400-1016-218
全國統(tǒng)一服務(wù)熱線
400-1016-218
科研好幫手 專業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁 > 產(chǎn)品中心 > 抗體 >> Anti -CD45 Rabbit pAb
Product Information
Description |
CD45 rabbit polyclonal |
Protein full name |
Receptor-type tyrosine-protein phosphatase C |
Synonyms |
PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD45 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
IHC |
Mouse, Rat |
1: 1000-1: 3000 |
spleen,lung,liver |
IF |
Mouse, Rat |
1: 2000-1: 4000 |
lymph node inflammation |
Background
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse liver using CD45(GB11066) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD45(GB11066) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse lung using CD45(GB11066) at dilution of 1: 1500 |
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse lymph node inflammation using CD31 (GB11063-2) at dilution of 1: 800 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室