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Anti -IL-1 beta Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101650
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

IL-1 beta rabbit polyclonal

Protein full name

Interleukin-1 beta

Synonyms

IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta

Immunogen

KLH conjugated Synthetic peptide

corresponding to human IL-1β 

Isotype

IgG

Purity

Affinity purification

Subcellular location

CytoplasmLysosomeSecreted

Uniprot ID

P01584P10749Q63264



Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1:800-1:1600

tonsillitis, pneumonia, inflammation lung, splenitis

IF

Human, Mouse, Rat

1:800-1:1600

lung



Background


Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.




Images



Immunohistochemistry analysis of paraffin-embedded human tonsillitis using 

IL-1β (GB11113) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using IL-1β (GB11113) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse inflammation lung using IL-1β (GB11113) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded rat splenitis using 

IL-1β (GB11113) at dilution of 1: 800

Immunofluorescent analysis of paraformaldehyde-fixed rat lung with LPS treated for 24h using IL-1β (GB11113) at dilution of 1: 800

Immunofluorescent analysis of paraformaldehyde-fixed mouse lung with LPS treated for 6husing IL-1β (GB11113) at dilution of 1: 800





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


Publications:



Title

Journal

Pubmed ID

Application

1

Early Enteral Nutrition Preserves Intestinal Barrier Function through Reducing the Formation of Neutrophil Extracellular Traps (NETs) in Critically Ill Surgical Patients.

Oxidative Medicine and Cellular Longevity

33294125

IHC

2

Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice.

International Immunopharmacology

33182020

IHC

3

QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism.

Cell Death & Disease

32382069

IHC

4

Induction of pathological changes and impaired expression of cytokines in developing female rat spleen after chronic excess fluoride exposure.

Toxicology and Industrial Health

30463494

IHC

5

Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis.

American Journal of Physiology - Gastrointestinal and Liver Physiology

30138574

IF

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