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Product Information
Description |
BCA1 rabbit polyclonal |
Protein full name |
C-X-C motif chemokine 13 |
Synonyms |
CXCL13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13, C-X-C motif chemokine ligand 13 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse BCA1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
spleen, brain, cerebellum |
IF |
Mouse, Rat |
1: 500-1: 1000 |
spleen, brain, cerebellum |
Background
CXCL13 is a small chemokine belonging to the CXC chemokine family. this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. In T lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T cell, particularly a subset of T cells called follicular B helper T cells (or TFH cells). Hence, expression of CXCL13 in T-cell lymphomas, such as Angioimmunoblastic T-cell Lymphoma, is thought to reflect a germinal center origin of the neoplastic T-cells.
Images
Immunohistochemistry analysis of paraffin-embedded mouse spleen using BCA1 (GB11919) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using BCA1 (GB11919) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat cerebellum using BCA1 (GB11919) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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