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Anti -BCA1 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101706
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

BCA1 rabbit polyclonal

Protein full name

C-X-C motif chemokine 13

Synonyms

CXCL13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13, C-X-C motif chemokine ligand 13

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse BCA1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

O55038




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1000-1: 2000

spleen, brain, cerebellum

IF

Mouse, Rat

1: 500-1: 1000

spleen, brain, cerebellum




Background


CXCL13 is a small chemokine belonging to the CXC chemokine family. this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. In T lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T cell, particularly a subset of T cells called follicular B helper T cells (or TFH cells). Hence, expression of CXCL13 in T-cell lymphomas, such as Angioimmunoblastic T-cell Lymphoma, is thought to reflect a germinal center origin of the neoplastic T-cells.




Images


Immunohistochemistry analysis of paraffin-embedded mouse spleen using

BCA1 (GB11919) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded mouse brain using

BCA1 (GB11919) at dilution of 1: 2000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using

BCA1 (GB11919) at dilution of 1: 2000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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