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Anti -MyD88 Rabbit pAb

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貨號:
DRF101738
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
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Product Information


Description MyD88 rabbit polyclonal
Protein full name Myeloid differentiation primary response protein MyD88
Synonyms MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88)
Immunogen KLH conjugated Synthetic peptide corresponding to Human MyD88
Isotype IgG
Purity Affinity purification
Subcellular location Nucleus, Cytoplasm
Uniprot ID Q99836, P22366, Q6Y1S1




Applications


Applications Species Dilution Positive Tissue
IHC Human, Mouse, Rat 1: 1200-1: 2400 small intestine, lung, pneumonia




Background

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.




Images



Immunohistochemistry analysis of paraffin-embedded human small intestine using MyD88 (GB111554) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded mouse lung using MyD88  at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat pneumonia using MyD88  at dilution of 1: 1200




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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