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Product Information
Description |
TLR7 rabbit polyclonal |
Protein full name |
Toll-like receptor 7 |
Synonyms |
Tlr7, UNQ248, PRO285 |
Immunogen |
Recombinant protein corresponding to Mouse TLR7 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
122 kDa |
Observed MW. |
122 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 1000-1: 2000 |
MCF7, Jurkat, 293T, THP-1, U87, U266 |
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Images
Western blot analysis of TLR7 (GB112633) at dilution of 1: 2000 Lane 1: MCF7 cell lysate Lane 2: Jurkat cell lysate Lane 3: 293T cell lysate Lane 4: THP-1 cell lysate Lane 5: U87 cell lysate Lane 6: U266 cell lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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