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Product Information
Description |
TLR9 rabbit polyclonal |
Protein full name |
Toll-like receptor 9 |
Synonyms |
TLR9, CD289, toll like receptor 9, Toll like receptor 9 isoform A precursor, Toll like receptor 9 isoform B |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse TLR9 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Lysosome, Membrane |
Uniprot ID |
Applications
applications |
species |
dilution |
Positive tissue |
IHC |
Human, Mouse |
1: 100-1: 500 |
tonsil, spleen |
IF |
Human, Mouse |
1: 100-1: 500 |
tonsil, spleen |
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response . Controls lymphocyte response to Helicobacter infection (By similarity).
Images
Immunohistochemistry analysis of paraffin-embedded human tonsil using TLR9(GB11266) at dilution of 1:200 |
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using TLR9(GB11266) at dilution of 1:400 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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