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Anti -Amyloid beta 40 Rabbit pAb

價格: 在線咨詢
貨號:
KT011513
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC
Species:
M,R
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

Amyloid beta 40 rabbit polyclonal antibody

Protein full name

Amyloid beta A4 protein

Synonyms

ABPP, APP, N-APP, Soluble APP-alpha, S-APP-alpha, C99, APP-C99, Abeta42, Abeta40, Beta-APP40, C83, APP-C59, Amyloid intracellular domain 59, APP-C57, Gamma-CTF(50), C31, App, Aβ40, Aβ42, A beta 40,beta Amyloid 40

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Aβ40

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell Membrane, Cytoplasm

Uniprot ID

P12023




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 400-1: 1000

brain




Background


Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particularly Aβ40—without increasing Aβ42 levels.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse brain using Aβ40 (GB111197) at dilution of 1:400 (180x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded mouse brain using Aβ40 (GB111197) at dilution of 1:400 (300x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded mouse brain using Aβ40 (GB111197) at dilution of 1:1000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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