KLH conjugated Synthetic peptide corresponding to Human Tau
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm, Cell membrane
Predicted MW.
79 kDa
Observed MW.
50-80 kDa
Uniprot ID
P10636, P10637, P19332
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 2000-1: 4000
brain, cerebral cortex, spinal cord, hippocampus
IHC
Human, Mouse, Rat
1: 1000-1: 2000
hippocampus, gliomas, brain, ganglion, brain
Background
Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.
Images
Western blot analysis of TAU
at dilution of 1: 3000
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse cerebral cortex tissue lysate
Lane 3: Mouse hippocampus tissue lysate
Lane 4: Mouse spinal cord tissue lysate
Lane 5: Rat brain tissue lysate
Lane 6: Rat cortex tissue lysate
Lane 7: Rat hippocampus tissue lysate
Immunohistochemistry analysis of paraffin-embedded human gliomas using TAU at dilution of 1: 1400
Immunohistochemistry analysis of paraffin-embedded mouse hippocampus using TAU at dilution of 1: 1400
Immunohistochemistry analysis of paraffin-embedded mouse brain using TAU at dilution of 1: 1400
Immunohistochemistry analysis of paraffin-embedded rat brain using TAU at dilution of 1: 1400
Immunohistochemistry analysis of paraffin-embedded rat ganglion using TAU at dilution of 1: 1400
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .