Anti - Tau Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011527

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

HMR/HMR/HMR

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Tau rabbit polyclonal
Protein full name	Microtubule-associated protein tau
Synonyms	Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, DDPAC, FTDP 17, MAPTL, RNPTAU, PPP1R103, Paired helical filament-tau
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Tau
Isotype	IgG
Predicted MW.	79 kDa
Observed MW.	50-80 kDa
Purity	Affinity purification
Subcellular location	Cytoplasm, Cell membrane
Uniprot ID	P10637, P19332, P10636

Applications

applications	species	dilution	Positive tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain
IHC	Human, Mouse, Rat	1: 100-1: 500	brain
IF	Human, Mouse, Rat	1: 100-1: 500	brain

Background

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Images

Western blot analysis of Tau(GB11178) at dilution of 1:1000

Lane 1: Mouse brain tissue lysate

Lane 2: Rat brain tissue lysate

Immunohistochemistry analysis of paraffin-embedded rat brain using Tau(GB11178) at dilution of 1:100

圖片 1.png

Immunohistochemistry analysis of paraffin-embedded human brain using Tau(GB11178) at dilution of 1:100

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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