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Product Information
Description |
Synphilin 1 rabbit polyclonal antibody |
Protein full name |
Synphilin-1 |
Synonyms |
Alpha-synuclein-interacting protein, Sncaip, Sph1, Synuclein alpha interacting protein |
Immunogen |
Recombinant protein corresponding to Mouse Synphilin 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Cytoplasm |
Predicted MW. |
106 kDa |
Observed MW. |
72 kDa |
Uniprot ID |
Q99ME3 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, brain, placenta |
IHC/IF |
Mouse, Rat |
1: 400-1: 2000 |
brain, heart |
Background
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.
Images
|
Western blot analysis of Sncaip (GB111991) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded mouse brain using Sncaip (GB111991) at dilution of 1: 650 (300x lens) |
Immunohistochemistry of paraffin embedded mouse heart using Sncaip (GB111991) at dilution of 1: 400 (400x lens) | |
|
Immunohistochemistry of paraffin embedded rat brain using Sncaip (GB111991) at dilution of 1: 400 (200x lens) |
|
Immunohistochemistry of paraffin embedded rat heart using Sncaip (GB111991) at dilution of 1: 650 (200x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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