Anti -Mint3 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011532

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Mint3 rabbit polyclonal antibody
Protein full name	Amyloid-beta A4 precursor protein-binding family A member 3
Synonyms	Adapter protein X11gamma, Neuron-specific X11L2 protein, Neuronal Munc18-1-interacting protein 3, Mint-3, Apba3, X11L2
Immunogen	Recombinant protein corresponding to Mouse Mint3
Isotype	IgG
Purity	Affinity purification
Predicted MW.	61 kDa
Observed MW.	61 kDa
Uniprot ID	O88888

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse	1: 500-1: 1000	liver, kidney

Background

The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the Beta-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11 Alpha (also designated Mint 1), X11 Beta (Mint 2) and X11 (Mint 3).

Images

Picture 1.png

Western blot analysis of APBA3 (GB112060) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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