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Anti -Mint3 Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT011532
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
M
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Mint3 rabbit polyclonal antibody |
|
Protein full name |
Amyloid-beta A4 precursor protein-binding family A member 3 |
|
Synonyms |
Adapter protein X11gamma, Neuron-specific X11L2 protein, Neuronal Munc18-1-interacting protein 3, Mint-3, Apba3, X11L2 |
|
Immunogen |
Recombinant protein corresponding to Mouse Mint3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
61 kDa |
|
Observed MW. |
61 kDa |
|
Uniprot ID |
O88888 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse |
1: 500-1: 1000 |
liver, kidney |
Background
The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the Beta-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11 Alpha (also designated Mint 1), X11 Beta (Mint 2) and X11 (Mint 3).
Images
|
|
Western blot analysis of APBA3 (GB112060) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室