Anti -NRG1 Rabbit pAb

價格：在線咨詢

貨號：

KT011533

產品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	NRG1 rabbit polyclonal antibody
Protein full name	Pro-neuregulin-1, membrane-bound isoform
Synonyms	Pro-NRG1, Neuregulin-1, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRGA, NDF, SMDF, HGL,HRG, Neu differentiation factor, Sensory and motor neuron-derived factor, NRG1, GGF
Immunogen	Recombinant protein corresponding to Human NRG1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	70 kDa
Observed MW.	55 kDa (mature); 72 kDa (precursor)
Uniprot ID	Q02297, P43322

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	lung

Background

The NRG1 was originally identified as a glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

Images

Picture 1.png

Western blot analysis of NRG1 (GB111258) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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