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Anti -FE65 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011538
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
HMR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

FE65 rabbit polyclonal antibody

Protein full name

Amyloid-beta A4 precursor protein-binding family B member 1

Synonyms

Protein Fe65, Apbb1, Fe65, Fe65 protein, RIR, Stat like protein, Amyloid beta A4 precursor protein binding family B

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse FE65

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm,  Nucleus

Uniprot ID

Q9QXJ1, P46933




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 100-1: 600

brain, kidney




Background


The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded mouse brain using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded mouse kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded rat brain using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded rat kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 6.png

Immunofluorescence of paraffin embedded human kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 7.png

Immunofluorescence of paraffin embedded mouse brain using APBB1 (GB112297) at dilution of 1:100 (400x lens)
Picture 8.png Immunofluorescence of paraffin embedded mouse kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 9.png

Immunofluorescence of paraffin embedded rat brain using APBB1 (GB112297) at dilution of 1:100 (400x lens)

Picture 10.png

Immunofluorescence of paraffin embedded rat kidney using APBB1 (GB112297) at dilution of 1:100 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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