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Product Information
Description |
CPLX3 rabbit polyclonal antibody |
Protein full name |
Complexin-3 |
Synonyms |
complexin 3, Complexin III, CPLX3, CPX III, CPXIII, Nbla11589 |
Immunogen |
Recombinant protein corresponding to Mouse CPLX3 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell junction |
Predicted MW. |
18 kDa |
Observed MW. |
20 kDa |
Uniprot ID |
Q8R1B5 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 1000-1: 2000 |
brain, eye |
IHC/IF |
Mouse |
1: 1000-1: 2000 |
cerebellum, frontal lobe |
Background
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (PubMed:19386896). Required for the maintenance of synaptic ultrastructure in the adult retina (PubMed:19386896). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (PubMed:15911881, PubMed:19386896, PubMed:27335398).
Images
|
Western blot analysis of CPLX3 (GB114074) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin embedded mouse cerebellum using CPLX3 (GB114074) at dilution of 1: 2000 |
|
Immunofluorescence of paraffin embedded mouse frontal lobe using CPLX3 (GB114074) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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