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Product Information
Description |
SOX10 rabbit polyclonal antibody |
Protein full name |
Transcription factor SOX-10 |
Synonyms |
Sox10, SOX10, DOM, PCWH, WS2E, WS4, WS4C, SRY-box 10 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SOX10 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Uniprot ID |
Q04888, O55170 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 500-1: 4000 |
brain, heart, small intestine |
Background
Transcription factor SOX-10 encoded by the SOX10 gene is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and determination of cell fate. The encoded protein act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. In melanocytic cells there is evidence that SOX10 gene expression may be regulated by MITF.
Images
Immunohistochemistry of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat heart using SOX10 (GB11782) at dilution of 1:2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse heart using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat small intestine using SOX10 (GB11782) at dilution of 1:500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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