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Product Information
Description |
Alpha-synuclein rabbit polyclonal |
Protein full name |
Alpha-synuclein |
Synonyms |
Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca, Syn |
Immunogen |
Recombinant protein corresponding to Mouse Alpha-synuclein |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
14 kDa |
Observed MW. |
18 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
hippocampus |
IHC |
Human, Mouse, Rat |
1: 1500-1: 3000 |
cerebellum |
ICC |
Human |
1: 800-1: 1600 |
SH-SY5Y |
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.
Images
|
Western blot analysis of Snca (GB112945) at dilution of 1: 1000 Lane 1: Mouse hippocampus tissue lysate Lane 2: Rat hippocampus tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded human oligodendrocytoma using Snca (GB112945) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using Snca (GB112945) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using Snca (GB112945) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using Snca (GB112945) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using Snca (GB112945) at dilution of 1: 3000 |
|
IImmunocytochemistry analysis of 4% paraformaldehyde-fixed SH-SY5Y cells using Alpha-synuclein GB112945 at dilution of 1: 1400 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
合肥萬物生物科技有限公司
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