Anti -Iba1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011571

產(chǎn)品規(guī)格：

100ul

Applications：

IHC/IF

Species：

H/M/R,H/M/R

品牌：

萬(wàn)物

購(gòu)買(mǎi)數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	Iba1 rabbit polyclonal
Protein full name	Allograft inflammatory factor 1
Synonyms	AIF-1, AIF1, G1, IBA1, IRT 1, Protein G1, Ionized calcium-binding adapter molecule 1, MRF1, Microglia response factor, BART 1, AIF1 protein
Immunogen	Recombinant protein corresponding to Mouse Iba1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Cytoplasm, Cytoskeleton, Cell projection
Uniprot ID	P55008, O70200, P55009

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse, Rat	1: 500-1: 1000	oligodendroglioma, brain, cerebellum
IF	Human, Mouse, Rat	1: 500-1: 1000	oligodendroglioma, brain, cerebellum

Background

AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1.

Images

	Immunohistochemistry analysis of paraffin-embedded human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse brain using iba1 (GB113502) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat brain using iba1 (GB113502) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat cerebellum using iba1 (GB113502) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed human oligodendroglioma using iba1 (GB113502) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using iba1 (GB113502) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat brain using iba1 (GB113502) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse cerebellum using iba1 (GB113502) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed rat cerebellum using iba1 (GB113502) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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