Anti -S100 beta Mouse mAb

價格：在線咨詢

貨號：

KT011583

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	S100 beta mouse monoclonal antibody
Protein full name	Protein S100-B
Synonyms	S100B, NEF, S100, S100-B, S100beta,S100 calcium binding protein B, S100β
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse S100B
Isotype	IgG1
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Uniprot ID	P50114, P04631, P04271

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 1000-1: 2000	brain, glioma

Background

S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS, it acts as a neurotrophic factor and neuronal survival protein. In the adult organism. it is usually elevated due to nervous system damage, which makes it a potential clinical marker.

Images

Picture 1.png

Immunohistochemistry of paraffin embedded human glioma using S100B (GB12359) at dilution of 1: 1000 (400x lens)

Immunohistochemistry of paraffin embedded mouse brain using S100B (GB12359) at dilution of 1: 1000 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded rat brain using S100B (GB12359) at dilution of 1: 1000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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