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Anti -FKBP52 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011605
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HM
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

FKBP52 rabbit polyclonal

Protein full name

Peptidyl-prolyl cis-trans isomerase FKBP4

Synonyms

51 kDa FK506 binding protein, 52 kDa FK506 binding protein, 52 kDa FKBP, 59 kDa immunophilin, FK506 binding protein 4, FKBP4, FKBP51, FKBP52, FKBP59, HBI, HSP binding immunophilin, Hsp56, Immunophilin FKBP52, p52, p59, PPIase, PPIase FKBP4, Rotamase

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse FKBP52

Isotype

IgG

Purity

Affinity purification

Predicted MW.

52 kDa

Observed MW.

55 kDa

Uniprot ID

Q02790P30416




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

293T, K562, A375, NIH/3T3




Background


FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia.




Images


圖片 1.png

Western blot analysis of FKBP52 (GB113168) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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