Anti -Phospho-TAU (S202/T205) Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011642

產(chǎn)品規(guī)格：

100 μL

Applications：

WB/IHC/IF

Species：

HMR/HMR

品牌：

萬(wàn)物

購(gòu)買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	Phospho-TAU (S202/T205) rabbit polyclonal antibody
Protein full name	Microtubule-associated protein tau
Synonyms	Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU, P-TAU
Immunogen	KLH conjugated Synthetic phosphopeptide corresponding to Human TAU (S202/T205)
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Cytoskeleton, Secreted, Cell membrane, Cell projection
Predicted MW.	79 kDa
Observed MW.	50-80 kDa
Uniprot ID	P10636-8

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, hippocampus, liver, spleen
IHC/IF	Human, Mouse, Rat	1: 600-1: 1200	brain

Background

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity .The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both .Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Images

	Western blot analysis of phospho-TAU (S202/T205) (GB113883) at dilution of 1: 1000
	Western blot analysis of phospho-TAU (S202/T205) (GB113883) at dilution of 1: 1000 The figure above was treated with phospho-blocking pepide, the figure below was treated with non-phospho- blocking pepide.
	Immunohistochemistry of paraffin embedded mouse brain using phospho-TAU (S202/T205) at dilution of 1: 1200

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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