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Anti -TTBK1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011646
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

TTBK1 rabbit polyclonal antibody

Protein full name

Tau-tubulin kinase 1

Synonyms

KIAA1855, TTBK1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TTBK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

142 kDa

Observed MW.

130 kDa

Uniprot ID

Q6PCN3




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse

1: 300-1: 800

brain, heart, testis




Background


TTBK1 (tau tubulin kinase 1), also known as BDTK (brain-derived tau kinase), is a 1,321 amino acid protein that contains one protein kinase domain and belongs to the serine/threonine protein kinase family. Localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord, TTBK1 functions as a serine/threonine kinase that can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Specifically, TTBK1 uses divalent cations, such as magnesium and manganese, to catalyze the ATP-dependent transfer of a phosphate group onto Tau, creating a phosphoprotein and ADP.




Images


Picture 1.png

Western blot analysis of TTBK1 (GB113900) at dilution of 1: 800




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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