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Anti -Alpha-synuclein Rabbit pAb

價格: 在線咨詢
貨號:
KT011652
產品規(guī)格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/MR
購買數(shù)量:
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產品詳情 操作說明 注意事項

Product Information


Description

Alpha-synuclein rabbit polyclonal antibody

Protein full name

Alpha-synuclein

Synonyms

SNCA, NACP, PARK1, PARK4, PD1, synuclein alpha, α-synuclein

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse α-synuclein

Isotype

IgG

Purity

Affinity purification

Subcellular location

CytoplasmMembraneNucleusSecreted

Predicted MW.

14 kDa

Observed MW.

19 kDa

Uniprot ID

P37840, O55042, P37377



Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 300-1: 600

brain, cerebral cortex

IHC/IF

Mouse, Rat

1:1000-1:2000

brain, cerebellum


Background


Alpha-synuclein is a protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain while smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells (neurons) in specialized structures called presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function.




Images



Picture 1.png

Western blot analysis of SNCA (GB11404) at dilution of 1: 300

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat brain using 

α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using 

α-synuclein GB11404 at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using 

α-synuclein GB11404 at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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