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Product Information
Description |
Neurturin rabbit polyclonal antibody |
Protein full name |
Neurturin |
Synonyms |
Nrtn, Neurturin precursor, prepro-neurturin, NTN |
Immunogen |
Recombinant protein corresponding to Mouse Neurturin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Secreted |
Uniprot ID |
P97463 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Mouse, Rat |
1: 500-1: 1600 |
brain |
Background
Neurturin and GDNF define a new family of neurotrophic factors. Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. NTN binds to and forms a complex with GFR-a-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway.
Images
|
Immunohistochemistry of paraffin embedded mouse brain using Neurturin (GB111577) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using Neurturin (GB111577) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using Neurturin (GB111577) at dilution of 1:1000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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