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Product Information
Description |
Collagen I rabbit polyclonal antibody |
Protein full name |
Collagen alpha-1(I) chain |
Synonyms |
COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
Immunogen |
Recombinant protein corresponding to Mouse COL1A1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Secreted |
Uniprot ID |
P11087, P02452, P02454 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1:800-1:1600 |
BDL model liver, kidney, liver cirrhosis, lung, skin |
Background
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.
Images
Immunohistochemistry of paraffin embedded human kidney using collagen I (GB11022-3) at dilution of 1:800 (200x lens) |
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Immunohistochemistry of paraffin embedded mouse skin using collagen I (GB11022-3) at dilution of 1:800 (200x lens)
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Immunohistochemistry of paraffin embedded mouse liver cirrhosis using collagen I (GB11022-3) at dilution of 1:800 (300x lens)
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Immunohistochemistry analysis of paraffin-embedded rat fibrosis liver using Collagen I (GB11022-3) at dilution of 1: 1600 |
Immunohistochemistry of paraffin embedded rat lung using collagen I (GB11022-3) at dilution of 1:800 (200x lens) | |
Immunofluorescence of paraffin embedded mouse BDL model liver using Collagen I (GB11022-3) at dilution of 1:1500 (200x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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