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Product Information
Description |
Desmin rabbit polyclonal antibody |
Protein full name |
Desmin |
Synonyms |
DES, CSM1, CSM2, LGMD2R, desmin |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse desmin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Cell membrane |
Predicted MW. |
54 kDa |
Observed MW. |
55 kDa |
Uniprot ID |
P31001, P48675 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 1000-1: 2000 |
heart |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 2000 |
endometrial cancer, metrocarcinoma |
Background
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures . May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.
Images
|
Western blot analysis of Desmin (GB11081) at dilution of 1: 1000 |
|
Immunofluorescence of paraffin embedded human endometrial cancer using Desmin (GB11081) at dilution of 1: 500 (400x lens) |
|
Immunofluorescence of paraffin embedded human metrocarcinoma using Desmin (GB11081) at dilution of 1: 500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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