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Product Information
Description |
E Cadherin rabbit polyclonal antibody |
Protein full name |
Cadherin-1 |
Synonyms |
CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO, cadherin 1, Epithelial Cadherin, E-Cadherin, CAM 120/80 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse E Cadherin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane, Cytoplasm |
Predicted MW. |
98 kDa |
Observed MW. |
135 kDa |
Uniprot ID |
P12830, P09803, Q9R0T4 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
spleen, lung, kidney |
IHC/IF |
Human, Mouse, Rat |
1: 200-1: 1500 |
colon, liver, prostate, stomach, uterus |
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Images
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Western blot analysis of E-cadherin (GB11082) at dilution of 1: 1000 |
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Western blot analysis of E-cadherin (GB11082) at dilution of 1: 1000 |
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Immunohistochemistry of paraffin embedded human liver using E-cadherin (GB11082) at dilution of 1: 1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human liver using E-cadherin (GB11082) at dilution of 1: 500 (350x lens)
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Immunohistochemistry of paraffin embedded human prostate using E-cadherin (GB11082) at dilution of 1: 500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse liver using E-cadherin (GB11082) at dilution of 1: 500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse stomach using E-cadherin (GB11082) at dilution of 1: 500 (300x lens) |
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Immunohistochemistry of paraffin embedded rat colon using E-cadherin (GB11082) at dilution of 1: 500 (300x lens) |
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Immunofluorescence of paraffin embedded mouse colon using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens) |
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Immunofluorescence of paraffin embedded mouse uterus using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens)
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Immunofluorescence of paraffin embedded rat stomach using E-cadherin (GB11082) at dilution of 1: 1900 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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