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Anti -ICAM1 Rabbit pAb
價格：
在線咨詢
貨號：
KT011890
產品規(guī)格：
100 μL
Applications：
WB/IHC/IF
Species：
HM/MR
購買數(shù)量：
產品詳情
操作說明
注意事項
Product Information
|
Description |
ICAM 1 rabbit polyclonal antibody |
|
Protein full name |
Intercellular adhesion molecule 1 |
|
Synonyms |
ICAM1, BB2, CD54, P3.58, intercellular adhesion molecule 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Membrane |
|
Predicted MW. |
58 kDa |
|
Observed MW. |
58 kDa |
|
Uniprot ID |
P05362, Q00238, P13597 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse |
1: 1000-1: 3000 |
kidney, liver,lung |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 5000 |
kidney, liver |
Background
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposis sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell .
Images
|
|
Western blot analysis of ICAM1 (GB11106) at dilution of 1: 1000 |
|
|
Immunohistochemistry of paraffin embedded mouse kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
|
|
Immunohistochemistry of paraffin embedded mouse liver using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
|
|
Immunohistochemistry of paraffin embedded rat kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室