Anti -Junctional Adhesion Molecule 1/JAM-A Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011900

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	JAM-A rabbit polyclonal antibody
Protein full name	Junctional adhesion molecule A
Synonyms	JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse JAM-A
Isotype	IgG
Purity	Affinity purification
Predicted MW.	33 kDa
Observed MW.	35 kDa
Uniprot ID	Q9Y624, O88792, Q9JHY1

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	liver, colon, small intestine

Background

Seems to play a role in epithelial tight junction formation. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin super family gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Images

Picture 1.png

Western blot analysis of Junctional adhesion molecule A (GB111062) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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