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Anti -Mesothelin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011925
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
M,R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

Mesothelin rabbit polyclonal antibody

Protein full name

Mesothelin

Synonyms

Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Msln, Mes, CAK1, SMR, SMRP, MAN

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Mesothelin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

49 kDa

Uniprot ID

Q61468, Q9ERA7




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

thymus, heart, lung, testis




Background


Mesothelin is a glycosyl-phosphatidylinositol-anchored glycoprotein present on the cell surface of various human solid tumors. It is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71kDa precursor protein that is processed to a 40kDa membrane-bound protein termed mesothelin and a 31kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues (e.g. mesothelium), and is expressed at high levels in mesotheliomas, as well as ovarian, pancreatic, and lung cancers. Mesothelin may be a new target for immunotherapy.




Images


Picture 1.png

Western blot analysis of mesothelin(CA125) (GB111016) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.



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