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Anti -RAB7 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011966
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

RAB7 rabbit polyclonal antibody

Protein full name

Ras-related protein Rab-7a

Synonyms

Rab7a, RAB7

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse RAB7

Isotype

IgG

Purity

Affinity purification

Predicted MW.

23 kDa

Observed MW.

23 kDa

Uniprot ID

P51149, P51150, P09527




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

kidney, lung




Background


Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events.Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts.




Images


Picture 1.png

Western blot analysis of RAB7A (GB111190) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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