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Anti -VEGFA Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012031
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

VEGFA rabbit polyclonal antibody

Protein full name

Vascular endothelial growth factor A

Synonyms

VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse VEGFA

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Predicted MW.

25 kDa

Observed MW.

43 kDa

Uniprot ID

P15692, Q00731, P16612




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, liver , kidney




Background


Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development .




Images


Picture 1.png

Western blot analysis of VEGFA (GB11034B) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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