NPM1 is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53. NPM1 may prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins. The NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins.
Images
Western blot analysis of Nucleophosmin (GB111375) at dilution of 1: 500
Immunohistochemistry of paraffin embedded human liver using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded human renal cancer using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded mouse placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded mouse testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded mouse thymus using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded rat placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded rat testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunohistochemistry of paraffin embedded rat thymus using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunofluorescence of paraffin embedded human prostate using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunofluorescence of paraffin embedded mouse placenta using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunofluorescence of paraffin embedded mouse testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Immunofluorescence of paraffin embedded rat testis using Nucleophosmin (GB111375) at dilution of 1: 1600 (400x lens)
Storage
Storage
Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).