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Anti -mTOR Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012201
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

mTOR rabbit polyclonal

Protein full name

Serine/threonine-protein kinase mTOR

Synonyms

FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human mTOR

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Predicted MW.

289 kDa

Observed MW.

289 kDa

Uniprot ID

P42345, Q9JLN9, P42346




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 400-1: 800

heart, liver, brain




Background


MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. MTOR has a calculated molecular mass of 289 kDa, and always can be detected at about 250 kDa due to some modifications.




Images


圖片 1.png

Western blot analysis of mTOR (GB111840)

at dilution of 1: 800

Lane 1: HEK293 cell lysate

Lane 2: HepG2 cell lysate

Lane 3: MCF7 cell lysate

Lane 4: Mouse heart tissue lysate

Lane 5: Mouse liver tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat heart tissue lysate

Lane 8: Rat liver tissue lysate

Lane 9: Rat brain tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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